Disulfiram and Lyme Disease
Compound medicine answers shortage of Disulfiram, a treatment for Lyme Disease
National Disulfiram Shortage
While Disulfiram tablets are on the FDA shortage list, Town & Country Compounding can make it for patients who are in need. We ship medications to 12 states, and Washington D.C. T&C Compounding can refer you to a prescriber in your area!
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What is Lyme Disease?
According to LymeDisease.Org:
“Lyme disease is a bacterial infection primarily transmitted by Ixodes ticks, also known as deer ticks, and on the West Coast, black-legged ticks. These tiny arachnids are typically found in wooded and grassy areas. Although people may think of Lyme as an East Coast disease, it is found throughout the United States, as well as in more than sixty other countries.” 1
Disulfiram inhibits the enzyme acetaldehyde dehydrogenase, leading to a buildup of acetaldehyde. It turns out disulfiram has known activity as an antimicrobial.
Dr. Liegner has reported the results of treating his first three patients with disulfiram in a recent article published in the journal “Antibiotics.”2 He now has over 30 patients on this treatment, and he is impressed with how highly effective it is for both Lyme disease and babesiosis.2
I have been practicing medicine long enough to be very skeptical of “breakthroughs.” But disulfiram may be the real thing. Let’s keep our fingers crossed.2
Daniel A. Kinderlehrer MD
Disulfiram & Lyme Disease Resources
Disulfiram–Breakthrough Drug for Lyme and Other Tick-Borne Diseases?
By Daniel A. Kinderlehrer MD
Since disulfiram has been shown to kill Plasmodium falciparum (malaria) in the laboratory, it is not surprising that it would also be effective against Babesia. Dr. Lewis is planning to do a study on mice infected with Bb. In addition, Dr. Brian Fallon at Columbia University has announced his intention to undertake a controlled trial using disulfiram in well-characterized patients with Lyme disease. (Click here for more information about the clinical trial.)
Disulfiram (Tetraethylthiuram Disulfide) in the Treatment of Lyme Disease and Babesiosis: Report of Experience in Three Cases
Three patients, each of whom had required intensive open-ended antimicrobial therapy for control of the symptoms of chronic relapsing neurological Lyme disease and relapsing babesiosis, were able to discontinue treatment and remain clinically well for periods of observation of 6–23 months following the completion of a finite course of treatment solely with disulfiram. One patient relapsed at six months and is being re-treated with disulfiram.
Low Dose Naltrexone & Lyme Disease
Over the years research has shown that LDN can be effective for patients with autoimmune disorders such as Crohn’s disease and Multiple Sclerosis. We are also working with physicians to incorporate LDN into protocols the utilize to treat Lyme Disease. It has been postulated that immune dysfunction could be a key to treating Chronic Lyme Disease.
At Town & Country Compounding, we care about patient education. We are here to provide you with resources and information on your treatment options.
*Northern New Jersey & NYC Area
Town & Country Compounding offers patients with integrative care. Patients have the option to learn more through a scheduled private consultation. The pharmacy can then get in contact with your physician and help find a treatment plan that fits your needs. We can ship out to you, just contact or call the pharmacy.
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