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Video: Low Dose Naltrexone (LDN) & Lyme Disease

Sourced from The LDN Research Trust

Lyme Disease Documentary with Mention of Low Dose Naltrexone (LDN)

What is Lyme Disease? How do you catch it? How to get an accurate diagnosis? How to treat it? How to live with it? What are options for alleviating symptoms?

Low Dose Naltrexone (LDN) is a treatment option that has grown globally in popularity for treating a variety of conditions, including lyme disease.

Contact Lyme Disease & LDN Expert Pharmacists 

Whether you are a patient suffering from Lyme Disease looking for insight on the treatment options from true experts, or if you are a health provider looking to find the right option for your patient- T&C Compounding Experts are here to help.

PCCA Article: Pharmacy Compounding & The U.S. Opioid Epidemic

By: A.J. Day Maria Carvalho

Pain affects more Americans than diabetes, heart disease and cancer combined. It represents an important public health issue that is associated with a wide range of injury and disease.1 As a result, an estimated 20% of patients with chronic pain receive an opioid prescription when visiting physician offices, and rates of opioid prescribing have grown significantly, in particular for family practice, general practice and internal medicine.2

The Epidemic
This has in turn contributed to further problems. Over two million people had an opioid-use disorder in 2016, translating to an economic burden of $504 million. On average, 116 Americans died every day from an opioid-related drug overdose.3 Today, the addictive properties and the potentially fatal risks of opioids have led to a nationwide public health emergency, as declared by the Acting Secretary of Health and Human Services on October 26, 2017.4

Prevention, assessment and treatment of pain can be challenging not only to patients and caregivers, but also to health care providers. The Centers for Disease Control and Prevention recommend nonopioid pharmacological treatments and nonpharmacological treatments as preferred for chronic pain (outside of active cancer, palliative, or end-of-life care).5

How Pharmacy Compounding Can Help 
Local compounding pharmacies are an integral part of their communities and are readily accessible to patients and physicians. For decades, compounding pharmacists have been helping patients with chronic pain by dispensing customized transdermal pain medications. While avoiding the use of addictive drugs, these medications may be customized to include different types of drugs, in various dosage strengths, that are delivered simultaneously in one application.

However, there are still many patients and health care providers who are unaware of this nonopioid treatment. Compounding pharmacists are in a unique position to help combat the opioid epidemic by suggesting transdermal pain medications to their patients and physicians. PCCA members in particular have access to a wide array of pain formulas with plenty of supporting literature on our PCCA Science page under Journal Articles > Lipoderm. Furthermore, PCCA members have access to a broad range of in-person and web-based compounding training and specialized support in pain management.

More recently, we co-authored an article published in the Journal of Opioid Management, titled “The Role of Transdermal Compounding in Opioid Safety.” It discusses the current U.S. opioid epidemic and explains how transdermal compounding can be a safe and effective therapeutic option for specific patients who need help with pain management.6 This article may be a useful scientific resource for patients and health care providers who are not yet familiar with the benefits of transdermal pain medications.

A version of this article was originally published the Summer 2018 issue of the Apothagram, PCCA’s quarterly, members-only magazine.

A.J. Day, PharmD, RPh, is the Director of Clinical Services at PCCA

Maria Carvalho, PharmD, MRPharmS, PhD, is the Manager of PCCA Science

1.    American Academy of Pain Medicine. (n.d.). AAPM facts and figures on pain. Retrieved from 
2.    Centers for Disease Control and Prevention. (2016). CDC guideline for prescribing opioids for chronic pain — United States, 2016. Morbidity and Mortality Weekly Report: Recommendations and Reports, 65(1). Retrieved from 
3.    U.S. Department of Health and Human Services. (2018). The opioid epidemic by the numbers in 2016 …. Retrieved from
4.    Hargan, E. D. (2017). Determination that a public health emergency exists. Retrieved from
5.    Centers for Disease Control and Prevention. (n.d.). CDC guideline for prescribing opioids for chronic pain. Retrieved from
6.    Bucher, C. V., Day, A. J., & Carvalho, M. (2018). The role of transdermal compounding in opioid safety. Journal of Opioid Management, 14(1), 17-22.

These statements are provided for educational purposes only. They have not been evaluated by the Food and Drug Administration, and are not to be interpreted as a promise, guarantee or claim of therapeutic efficacy or safety. The information contained herein is not intended to replace or substitute for conventional medical care, or encourage its abandonment.

Do You Need a Referral to a Lyme Disease Prescriber?

T&C Compounding works with the most prestigious providers. We work with you and health providers/specialists to formulate the most customized medication regimens to fit your specific needs. Medication is not one-size-fits-all, our compounding specialists use precise compounding techniques & equipment to get you the best solution.