Sterile Compounded Ophthalmic Medications
Town & Country Compounding specializes in compounded ophthalmic medications
Town & Country Compounding compounds the high quality sterile compounds your patients need. Whether the compounds are needed for surgical procedure, serious infections or drops that are used daily, we compound the quality they deserve.
Commonly Prescribed Eyedrops
Atropine Eye Drops (Low-Dose For Pediatric Patients)
Atropine Eye Drops (Low-Dose For Pediatric Patients)
Related blog: Atropine Eye Drops for Children with Nearsightedness (Myopia) >>
The strength of eye drops needed for children with myopia is not commercially available. A compounding pharmacist can use the higher-strength commercial product and dilute it for the pediatric patient. This is done only in a sterile compounding lab.
Sometimes a patient needs a compounded medication to be administered at the surgery center for a procedure.
*These are compounded with a prescription for a specific patient
Autologous Serum Eye Drops (ASED)
Autologous Serum Eye Drops (ASED)
Autologous serum eye drops are often requested when patients have not had success with various medications for chronic dry eyes. Their own serum is used to make their eye drops.
How Autologous Serum Eye Drops (ASED) Work
Conventional therapies for severe dry eyes fail to heal the epithelial cells, which are the cells on the top layer of the cornea. The dry epithelial cells sometimes fall off of the cornea easily. Autologous serum comes from the patient’s own blood serum and plasma (Source: clevelandclinic.org).
The fluid contains epithelium-promoting growth factors and becomes a good replacement for tears.
Sjogren’s syndrome is an inflammatory condition in which the mucous membranes, especially in the nose and mouth become very dry. Sometimes you will see this in patients who have rheumatoid arthritis and lupus.
Autologous serum eye drops (ASED) are thought to contain various growth factors and nutrients from the serum that benefit the surface of the eye and may help with corneal epithelial defects. Serum contains albumin, vitamin A, and nerve and epidermal growth factors that may promote healthy growth and healing of the ocular surface. These nutrients are not in over-the-counter artificial tears preparations.
They are sometimes used by doctors with patients with neuropathic eye pain, keratitis and may also be used before and after certain high-risk corneal transplants and SLET procedures, or for post-vitrectomy diabetics.
Fortified Antibiotic Eye Drops
Fortified Antibiotic Eye Drops
Eye drops are often needed at a higher strength than what is commercially available for certain conditions and therefore, must be prepared by a compounding pharmacy. Often, the alternative to fortified ophthalmic drops is hospitalization and Intravenous infusions. It is important to get these eye drops to the patient very quickly when needed!
Timely intervention will help the most resistant microbial keratitis and prevent the need for surgical intervention
The conditions that may require fortified eye drops:
- Resistant microbial keratitis – This diagnosis is considered an emergency situation.The infection can progress rapidly and can progress quickly and can cause permanent damage that decreases vision. Around 30,000 cases of microbial keratitis occur annually in the U.S.
- Corneal ulcers
- Bacterial infections on the ocular surface
Read more:
– Common Eye Infections
– The Pharmacist’s Role in Managing Microbial Keratitis
Commonly prescribed eye drops
Tobramycin Fortified Ophthalmic Solution
- We can compound strengths 13 mg/mL-15 mg/mL (BUD = 14 days)
- Refrigeration Required
Vancomycin Fortified Ophthalmic Solution
- We can compound strengths 12.5 mg/mL, 14 mg/mL, 25 mg/mL, 50 mg/mL (BUD = 14 days)
- Refrigeration Required
Other anti-microbial ophthalmic medications:
- Amikacin (2.5%)
- Cefazolin (50 mg/mL)
- Ceftazidime (5%)
- Chlorhexidine Digluconate (0.02% – 1%)
- Polyhexamethylene Biguanide (PHMB) (0.02%)
- Voriconazole (0.1 – 1%)
Additional ophthalmic medications we commonly compound:
- Acetylcysteine (5%, 10%)
- Albumin (4%, 5%)
- Atropine (0.01%, 0.02%, 0.025%, 0.1%, 0.125%)
- Cyclosporin MCT (0.1%-0.5%, 1%, 2%)
- Dexamethasone (0.01%, 0.1%)
- Glycerin (50%)
- Mitomycin (0.02% – 0.04%)
- Prednisolone (1%)
- Timolol (0.5%)
Intravitreal injection examples
- Ganciclovir
- Amikacin
- Clindamycin
- Dexamethasone
- Methotrexate
- Vancomycin
- Voriconazole
- Ceftazidime
- Amphotericin B
- tPA
Other ophthalmic compounds
- Brilliant blue
- PF Tropicamide
- Losartan
- Betadine syringes (single unit dose)
- Mitomycin
- Phenylephrine /tropicamide /ofloxacin /tetracaine / flurbiprofen syringes (P10 eye drops) or custom combinations
- Lidocaine/epinephrine/BSS (Shugarcaine) syringes or vials
Sterile Compounding Standards
Town & Country Compounding Is Compliant and goes beyond the requirements of USP 795, USP 797, and USP 800 Guidelines
Our profession has adopted new rules and regulations from the State Board of Pharmacy and the USP (United States Pharmacopeia). We are USP 800 compliant with all aspects as a sterile and non-sterile 503A compounding pharmacy.
Town & Country Compounding Sterile Lab Suite
The sterile lab suite at Town & Country Compounding has multiple labs (ISO certified rooms) where injectable medications, intravenous (IV) solutions, ophthalmic eyedrops, intravitreal injections, intrathecal infusions for targeted drug delivery, and other sterile medications are prepared.
The labs (ISO certified rooms) are separated depending on the types of drugs that are compounded in each, positive pressure rooms for non-hazardous sterile medication and negative pressure rooms for hazardous sterile medication.
- USP 797 (ISO 7 certified positive pressure buffer room) (non-hazardous drugs)
- USP 797 ISO 8 positive pressure ante room
- USP 797/800 (ISO 7 certified negative pressure Buffer room)
(hazardous drugs) - USP 797/800 (ISO 7 certified negative pressure ante room (hazardous drugs)
- ISO 8 certified positive pressure hand scrubbing and gowning room
Let us show you how we make ours.
Take a tour of our high-tech sterile compounding labs.
Where you get your medicine compounded makes a big difference in your health outcomes.
Town & Country Compounding makes customized medicine to the highest standards.
Experts in Sterile Compounded Ophthalmic Prescriptions
Prescribers:
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We are licensed to fill and ship prescription medications to multiple states
Ophthalmology: Blogs & Articles
