Methylene Blue: Lyme Disease and Bartonella
Quality of compounded methylene blue capsules is important.
Methylene blue is prescribed in various dosage forms for different conditions in medicine, yet when practitioners want to prescribe capsules, patients have a hard time finding them. The capsule form of methylene blue isn’t commercially manufactured by a drug company, therefore, it won’t be found at standard “big box” retail pharmacies. Methylene blue should be compounded at a high-quality compounding pharmacy, one that is PCAB certified.
It is important to use a pharmacy that is experienced in compounding and uses the highest quality chemicals in compounding, meaning you should verify they are using methylene blue, USP grade, not another technical grade of methylene blue. At Town & Country Compounding, we compound methylene blue on a regular basis, 50-mg capsules are common, but other strengths may be prescribed.
At Town & Country Compounding Pharmacy, we can compound methylene blue capsules, fill prescriptions, and ship directly to patients in multiple states.
Methylene Blue and Lyme Disease Information
The practitioner in the video discusses methylene blue and its different applications in medicine, such as in methemoglobinemia.
Lyme Disease, Bartonella, and Methylene Blue
Dr. Todd Maderis discusses the characteristics of the different phases of Lyme disease: lag, log (growth), stationary, and death. The bacteria that causes Lyme disease is Borrelia burgdorferi, yet an infection that often accompanies Lyme disease and can cause more distressing symptoms for the patient is Bartonella. This co-infection is difficult to diagnose and very hard to eradicate. While Lyme disease is transmitted mainly by a tick, Bartonella has many vectors.
Effect of different drugs and drug combinations on killing stationary phase and biofilm recovered cells of Bartonella henselae in vitro
Results for various antibiotic combinations were evaluated after six days, including azithromycin/methylene blue and rifampin/methylene blue”; their potential for eradication of B. henselae is discussed.
“Biofilms are colonies of bacteria that improve other bacteria’s ability to survive. None of the single or combination antibiotics were able to kill Bartonella after 2 and 4 days but azithromycin/ciprofloxacin, azithromycin/methylene blue, rifampin/ciprofloxacin, and rifampin/methylene blue combinations eradicated Bartonella in biofilms after six days.” Source: Antibiotics
Methylene Blue and Serotonin
Because of the potential risk of a life-threatening condition called Serotonin Syndrome, methylene blue should not be used when a patient is on SSRIs, SNRIs, or drugs that increase serotonin levels.
Methylene Blue: Some Possible Indications, Side Effects, Warnings
- arm or leg pain
- blue or green urine
- skin discoloration
- altered taste
- the sensation of feeling hot
Methylene Blue Compounded Capsules
Methylene Blue is compounded by a PCAB accredited pharmacy. This compounded medication requires a prescription.
See info about Methylene blue and Alzheimer’s disease research
See info about LDN and Lyme disease
More information on Bartonella
Effect of different drugs and drug combinations on killing stationary phase and biofilms recovered cells of Bartonella henselae in vitro
Efficacy of Double-Dose Dapsone Combination Therapy in the Treatment of Chronic Lyme Disease/Post-Treatment Lyme Disease Syndrome (PTLDS) and Associated Co-infections: A Report of Three Cases and Retrospective Chart Review
Information about the drug interaction between Methylene Blue and serotonergic medications
Methylene Blue: Indications, Side Effects, Warnings