Anal fissures are a pain in the butt! Literally. T&C Compounding formulates the most advanced treatments to relieve pain, allowing comfort during the healing process.
Anal Fissures are a Pain in the Butt!
Causes, Symptoms & Treatment of Anal Fissures
What’s an Anal Fissure?
An anal fissure is a small tear in the thin tissue (mucosa) that lines the anal canal. Anal fissures are typically the result of some form of trauma to the anus. This trauma has been associated with a variety of causes, but most often is simply the result of a hard stool.
At Town & Country Compounding we do the best to work with the patient and the practitioner to offer other options for the patients.
*Northern New Jersey & NYC Area
What Causes Anal Fissure Pain?
- The initial pain of an anal fissure will cause the internal anal sphincter muscle to tighten and go into spasm.
- This spasming of the sphincter muscle aggravates the fissure causing extreme pain during and after a bowel movement.
- The tightening/spasming of the sphincter muscle also restricts blood flow to the affected area, which delays healing.
How to Eliminate Fissure Pain
The key to anal fissure pain relief is keeping the Internal Anal Sphincter Muscle in a relaxed state. Keeping the Internal Anal Sphincter Muscle relaxed and preventing spasm will significantly reduce pain and improve blood flow to the affected area to promote healing. Patients comment that after using DoseRite, they think their fissure is healed after the first few days because their pain is gone. The goal is to keep patients pain-free while their fissure heals (usually 4-6 weeks to heal).
What Medications Are Being Used?
Topical calcium channel blockers (e.g. Nifedipine, Diltiazem) work by relaxing the sphincter muscle and increasing blood supply to the fissure. They are designed to be applied to the anal mucosa (soft lining of the anal canal) where it can be absorbed by the internal anal sphincter muscle.
- Rubbing the medication on the outside of the anus is not effective at reaching internal anal sphincter muscle.
- Intra-anal application makes a difference. Most patients don’t want to or can’t insert their finger into their fissured anus.
- Getting the correct dose is also important. A pea-size amount is not enough to relax the internal sphincter muscle.
Note from T&C Compounding: Compounded formulations are often prescribed because certain drugs are not commercially available in a topical form or in combination form. For example, nifedipine, which is normally only an oral drug, can be compounded into a rectal ointment. Also, it is very common for a prescriber to request for something for pain to be added into the formulation. One commonly requested mixture is nifedipine + lidocaine.
Intra-Anal Application with DoseRite
(available at Town & Country Compounding with your Rx)
- The goal of DoseRite is to eliminate pain while the fissure heals.
- DoseRite’s intra-anal applicator is designed to deliver medication within the anal canal, NOT the rectum. Its closed-end design prevents medication delivery into the rectum.
- Medication is delivered within the anal canal and is absorbed by the anal mucosa- the soft tissue surrounding the internal anal sphincter muscles (see DoseRite graphic).
- Intra-anal application with DoseRite improves pain relief over peri-anal application with a finger1.
- Intra-anal application with DoseRite also reduced side effects
- such as headaches with patients using Nitroglycerine (NTG)1.
- Side slots deliver medication along the length of the tip.
- Safety flange ensures applicator is always inserted to a safe depth.
Town & Country Compounding offers customized medications and can help you find solutions that work via a scheduled private consultation. The pharmacy can then get in contact with your physician and help find a treatment plan that fits your specific needs.
We can ship out to you just email or call the pharmacy.