Methylcobalamin (RG3-Synapsin®) Spray & Inflammation

T&C Compounding – Experts in the Compounding Methylcobalamin (RG3-Synapsin®) Spray

Methylcobalamin (RG3-Synapsin®) Spray

Rg3 is one of several triterpene saponins (ginsenosides) found in the plant genus Panax, including Panax ginseng (Asian ginseng) and Panax quinquifolius (American ginseng). Laboratory studies report that Rg3 extracted from Panax ginseng supports neuroprotection, helping to support healthy microglial activity and healthy neuronal function.

quells inflammation, gets neurons to bud (and refueled),and gets the mitochondria to calm down the microglia.
triggers mitochondrial rejuvenation -mitochondria become fully active and generate energy in the brain
helps with sirtuins (SIRT1’s) which are regulators of metabolism.
improves receptor activation. Often, when you give supplements or hormones, the results are affected by the receptors and how active they are.

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How can we quiet that brain cell activation which leads to inflammation?
According to Dr. James LaValle, RG3 and Nicotinamide Riboside may help.

See NBC News Report Linking Alzheimer’s Disease & CNS Inflammation

What do we know about inflammation?

Stress causes people to feel scattered and feeling like they can’t think straight. They often wonder what is happening to them.

Neuroinflammation is an inflammation of the central nervous system (CNS). It can lead to neuronal injury and dysfunction.

What can lead to neuroinflammation?

Traumatic brain injuries (Concussions, motor vehicle accidents, injury from violence)
Autoimmune diseases
By-products of diseases- circulating endotoxins
Microglial activation- different components to inflammation are led by microglial cells
Chronic stress- Chronic stress involves elevated cortisol which can lead to microglial activation via the release of inflammatory cytokines. In other words, stress often causes chronic inflammation which can lead to neuronal injury or death and therefore changes in behavior. It interferes with all stages of neuronal renewal.

Possible Causes of Inflammation

Traumatic Brain Injuries, examples

Dr. James LaValle: Director of the NFL Hall of Fame Center for Excellence for research on traumatic brain injuries.

NFL players with concussions (as well as many other sports)
Military people such as Navy Seals after being in combat zones
Motor Vehicle Accidents
Electric Shock
Violence Injury

Disease

Diabetes
Parkinson’s
Alzheimer’s (Dementia)
Autism Spectrum Disorder
ADHD
Autoimmune Diseases
ALS (Lou Gehrig’s Disease)
Lyme Disease
Mold
Stroke /TIA’s

Chronic Stress Situations

Executive Burnout
Career stress—see an example of racecar drivers
Lifestyle stress- money, marriage, kids
Overloaded parents with “jello brain”

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