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Low Dose Naltrexone (LDN) Resources
Featured LDN Review Article: The Use of Low-Dose Naltrexone (LDN) as a Novel Anti-Inflammatory Treatment for Chronic Pain

Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells.

This review covers the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.

*Younger, J., Parkitny, L., & Mclain, D. (2014). The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain. Clinical Rheumatology, 33(4), 451-459. doi:10.1007/s10067-014-2517-2

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Dr. Asher Goldstein
Board Certified Physician Specializing in Pain Management and Opioid Detox

Learn About LDN From an Experienced Physician

Get insight from providers that prescribe Low Dose Naltrexone (LDN) for their patients.

Low Dose Naltrexone (LDN) Presentation/Pain Management and Immune Dysfunction Diseases

(43 minutes)

Blogs on Low Dose Naltrexone (LDN)

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