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Perio Gel X®

Perio Gel® added a new formulation to their line, which we now have in stock
it’s saccharin-free and has xylitol instead.

  • $25/tube
  • $22/tube (when you buy 6 or more)

Interested in Purchasing?

This is an over-the-counter product, therefore we can ship anywhere.

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Hydrogen Peroxide

The active ingredient  in PerioGelX is hydrogen peroxide. It occurs naturally in the body and is  also a powerful antimicrobial. Hydrogen peroxide penetrates the  protective slime layer covering bacterial communities, and it can break  down the cell walls of bacteria causing infections and oral wounds  associated with gum diseases like gingivitis and periodontitis.

These  infections and oral wounds are hard to see because they are hidden  below the gum tissue. Getting medication under the gums and keeping it  there long enough to work can be a challenge. Research shows that a  customized prescription Perio Tray can deliver and maintain PerioGelX  below the gum tissue long enough for the hydrogen peroxide to do its  work.

The Perio Tray is specifically designed to place medication  in the periodontal pocket, the space between tooth and gum tissues that  harbors infections. The Perio Tray is truly unique, fabricated with a  seal system customized for each tooth according to patient conditions.  The seal prevents leakage and directs the medication in the pocket.

Tooth Whitening

A  common side effect of PerioGelX usage in prescription trays is gradual  tooth whitening. Patients who have anterior restorations (for example  crowns in front teeth) should talk with their doctors/dentists. The 1.7%  concentration of hydrogen peroxide in PerioGelX is much lower than  professional whitening products, so whitening effects will not be  immediately noticed, but with consistent usage gives you a whiter,  brighter smile.

What Else Should I Know?

With any treatment for  home use, it is important to follow the schedule prescribed by your  doctor/dentist. Periodontal disease is never cured. Bacterial  communities underlying the disease can begin to reform within days. The  most advanced stage of bacterial growth involves clumps of bacteria  detaching from the original community to form new infections.

Most  people don’t even know they have a problem because the infections are  hidden from view. Left unchecked, gum disease can lead to bad breath,  bleeding gums, and tooth loss.

Professional dental cleanings are  important to remove bacterial communities causing the disease, but  additional care is often recommended to help manage bacterial regrowth.  Research shows that when professional cleanings are combined with Perio  Tray delivery of PerioGelX, the results are significantly better.

Once  you have the disease under control, it is important to continue with  maintenance treatment as prescribed by your doctor/dentist. Keeping oral  bacteria in check can protect you from the disease recurrence.

For Best Results

Store  PerioGelX away from sunlight at room temperature (do not freeze or  refrigerate). For better control dispensing the gel, snip the end tip of  the tube.


Hydrogen peroxide mouth rinse and povidone iodine mouth rinse have been shown to break the layer of fat on the virus that protects the viral RNA, which is important for replication of the virus once it gets in the cells. The assumption is that these types of mouth rinses kill the virus.



Hydrogen Peroxide and Viruses
Milton V. Marshall, PhD, DABT, RQAP-GLP, CCRP*