Topical Losartan Opthalmic Eye Drops photo

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Topical Losartan Opthalmic Eye Drops

Losartan is only commercially available in tablet form, there is not an ophthalmic form available. Commercial tablets may not be used to compound a sterile product. Only experienced, high quality compounding pharmacies should compound losartan topical for the eye.

Dr. Wilson’s article in the Journal of Ocular Pharmacology and Therapeutics includes conditions that should be examined, including:

“Corneal scarring fibrosis due to: 

  • Lacerations
  • Refractive surgery complications, such as PRK late haze or complicated LASIK or SMILE
  • Viral infections, such as herpes simplex keratitis and herpes zoster ophthalmicus
  • Bacterial, fungal or acanthamoeba keratitis
  • Epidemic keratoconjunctivitis scars
  • Chemical burns
  • Endothelial corneal graft displacement
  • TGF beta-induced corneal dystrophies
  • Conjunctival fibrotic diseases, such as trachoma and Stevens-Johnson syndrome
  • Glaucoma surgery complications, such as conjunctival bleb scarring and shunt encapsulation
  • Hypertrophic skin scars on eyelids and in the periocular area “
 

Source : Cleveland Clinic

Topical Losartan: Practical Guidance for Clinical Trials in the Prevention and Treatment of Corneal Scarring Fibrosis and Other Eye Diseases and Disorders https://pubmed.ncbi.nlm.nih.gov/36877777/