The Ozempic®, Wegovy®, Mounjaro® shortages affect patients’ health.
Town & Country Compounding provides alternatives they need.
“Do you have Ozempic®? Do you have Wegovy®? Do you have Mounjaro®?”
At Town & Country Compounding, we get asked this question every day due to the nationwide shortages of these drugs.
These injectable drugs, (Ozempic®, Wegovy®, and Mounjaro®), utilized in diabetes and/or weight loss, are often on the FDA drug shortage list which makes access for patients very limited. When the drugs appear on the FDA drug shortage list, sterile compounding pharmacies are allowed to compound semaglutide and tirzepatide injections, yet they are not considered generics.
As the media has recently reported, it is very important to use only a high-quality compounding pharmacy and research the pharmacy where your sterile compounded medications come from. The compounding pharmacy should be using an outside lab to test sterility and endotoxins of the semaglutide or tirzepatide made in their lab.
The FDA has specific guidelines about compounding semaglutide and tirzepatide; and as an accredited compounding pharmacy, Town & Country Compounding strictly adheres to those guidelines.
Doctors Trust Town & Country Compounding for High-Quality Compounded Medications
Where you get compounded medications makes a big difference in health outcomes.
Unlike commercial drugs from a retail pharmacy (that will have the same quality no matter where you buy them), the quality and effectiveness of compounded medications can vary widely from pharmacy to pharmacy.
Do you know how your sterile compounded medicines are made?
See our sterile compounding labs and accreditations.
What is the difference with these injectable drugs?
- Semaglutide (the active ingredient in Ozempic® and Wegovy®) works as an agonist on only the GLP-1(Glucagon-like Peptide-1) receptor.
- Tirzepatide (the active ingredient in Mounjaro®) — dual receptor agonist, works on the GLP-1 receptor and the GIP (Glucose Dependent Insulinotropic Polypeptide, also known as Gastric Inhibiting Polypeptide) receptor. *Activation of both types of receptors enhances the glucose-lowering effects which may provide additional benefits in terms of weight loss and blood sugar control.
Semaglutide primarily stimulates the GLP-1 receptor, leading to increased insulin release, reduced glucagon secretion, slowed gastric emptying, and increased feelings of fullness, and it is used to improve blood sugar control and, in higher doses, for weight management.
*Activation of the GLP-1 receptor leads to several beneficial effects with both semaglutide and tirzepatide
- Increased insulin release
- Reduced glucagon secretion
- Slowed gastric emptying and increased feelings of fullness
- Decreased hunger through satiety pathways
- Up-modulates fat utilization
- Reduced ghrelin levels in stomach/gut
Tirzepatide has a dual mechanism of action through the GLP-1 and GIP receptor agonist. Its dual action makes it distinct from medications like semaglutide, which primarily target the GLP-1 receptor alone.
Potential benefits of tirzepatide with dual receptor agonist action:
- additional weight loss benefits
- additional blood sugar control
*Activation of the GIP receptor (Glucose Dependent Insulinotropic Polypeptide, also known as Gastric Inhibiting Polypeptide)
- If used alone: Increases glucagon secretion — risky for T2D but when used in combination with a GLP-1R, down regulates glucagon levels.
- In combo with GLP-1R: enhances appetite suppression and improves WAT (white adipose tissue) health and storage capacity, thereby reducing lipid ‘spillover’ and ectopic fat accumulation (around organs: heart, liver, kidneys, etc).
It's easy to prescribe semaglutide and tirzepatide with Town & Country Compounding
Nutritional Support for Patients on Ozempic & Wegovy (Semaglutide & Tirzepatide Injection)
Patients using Ozempic, Wegovy, compounded semaglutide and tirzepatide, can find helpful nutritional support products at Town & Country Compounding.
Deciding which vitamins and supplements to use during the weight loss process is always a popular topic of discussion. Whether patients are diabetic or not, they can benefit from being aware of options for nutrition support.
A professional supplement line (available only to medical professionals), Ortho Molecular, has developed a protocol to help support patients that are using Ozempic, Wegovy, and compounded semaglutide injections.
Read our step-by-step guide to semaglutide nutritional support.