DoseRite Rectal Administration Device

Keep the internal sphincter muscle relaxed by applying topical medications such as Diltiazem, Nifedipine or Nitroglycerine to the tissue surrounding the anal sphincter muscle (anoderm) in the anal canal.¹ Studies show that applying these medications in the anal canal is more effective at relaxing the internal sphincter muscle than application around the outside of the anus.²  Delivery into the rectum should also be avoided for effective relief.