Injectable Tirzepatide
Tirzepatide has a dual mechanism of action through the GLP-1 and GIP receptor agonist. Its dual action makes it distinct from medications like semaglutide, which primarily target the GLP-1 receptor alone.
Details
Tirzepatide
Potential benefits of tirzepatide with dual receptor agonist action:
- additional weight loss benefits
- additional blood sugar control
*Activation of the GIP receptor (Glucose Dependent Insulinotropic Polypeptide, also known as Gastric Inhibiting Polypeptide)
- If used alone: Increases glucagon secretion — risky for T2D but when used in combination with a GLP-1R, down regulates glucagon levels.
- In combo with GLP-1R: enhances appetite suppression and improves WAT (white adipose tissue) health and storage capacity, thereby reducing lipid ‘spillover’ and ectopic fat accumulation (around organs: heart, liver, kidneys, etc).
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