Call Now (201) 447-2020 |   Get Directions  |  Refills

NBC News Report Linking Alzheimer’s Disease & CNS Inflammation

T&C Compounding – Experts in the Compounding of LDN

Brain (CNS) Inflammation

Recently, NBC News released a fascinating report linking central nervous system inflammation and Alzheimer’s. If true, is the first truly “attackable” angle to help prevent and potentially mitigate the symptoms of Alzheimer’s.

 

This could hold opportunities to advance and focus medication development towards neuroinflammation.

 

What Can Lead to Neuroinflammation?

  • Traumatic brain injuries (Concussions, motor vehicle accidents, injury from violence)
  • Autoimmune diseases
  • By-products of diseases- circulating endotoxins
  • Microglial activation- different components to inflammation are led by microglial cells
  • Chronic stress- Chronic stress involves elevated cortisol which can lead to microglial activation via the release of inflammatory cytokines.  In other words, stress often causes chronic inflammation which can lead to neuronal injury or death and therefore changes in behavior. It interferes with all stages of neuronal renewal.
    • Stress causes people to feel scattered and feeling like they can’t think straight. They often wonder what is happening to them.

How can we quiet that brain cell activation which leads to inflammation?
According to Dr James LaValle,  RG3 and Nicotinamide Riboside may help.

Low Dose Naltrexone (LDN)

Read about the mechanism in which low dose naltrexone LDN works to reduce inflammation.

Review Article: Low Dose Naltrexone (LDN) & Inflammation

Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells. These effects may be unique to low dosages of naltrexone and appear to be entirely independent from naltrexone’s better-known activity on opioid receptors. As a daily oral therapy, LDN is inexpensive and well-tolerated. Despite initial promise of efficacy, the use of LDN for chronic disorders is still highly experimental. Published trials have low sample sizes, and few replications have been performed. We cover the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.

What is Low Dose Naltrexone (LDN)?

Naltrexone belongs to a class of drugs known as opioid antagonists. Naltrexone blocks opiate drugs from binding to the opioid receptors, which can result in increased endorphin and enkephalin release. Therefore, this results in reduced: 1. signaling and release of inflammatory substances, 2. nerve cell inflammation and 3. autoimmune mediators.

What About Low Dose Naltrexone (LDN)?

Low Dose Naltrexone (LDN), may be exceptionally good at reducing neuroinflammation, to the point where it could accomplish symptom reductions for neurological diseases and conditions that aren’t possible with other medications.

Speak to T&C Compounding Experts to learn more about LDN and if it could be the right fit for you or your loved one.

John Herr, PCCA Advisory Council, Owner of T&C Compounding PharmacyJohn Herr, PCCA Advisory Council, Owner of T&C Compounding Pharmacy

LOW DOSE NALTREXONE (LDN) EXPERT:
JOHN HERR, RPh.

Expert Pharmacist John Herr, RPh has worked with researchers, physicians, and patients worldwide to become an expert in proper titrations & dosage of Low Dose Naltrexone (LDN).

Learn More About LDN

Do You Need a Referral to a Low Dose Naltrexone (LDN) Prescriber?

T&C Compounding works with the most prestigious providers. We work with you and health providers/specialists to formulate the most customized medication regimens to fit your specific needs. Medication is not one-size-fits-all, our compounding specialists use precise compounding techniques & equipment to get you the best solution.

""
1
Please provide your Information to receive a list of
T&C's trusted providers, who can help you get the prescription you need.
Full Name
I Need a Prescription for:
Location (City, State)
Previous
Next

Low Dose Naltrexone (LDN) FAQ

Frequently Asked Questions

It’s important to ask questions when researching medications, especially when it comes to pain relief. Many individuals looking for alternatives to addictive opioids have found Low Dose Naltrexone (LDN) can be the solution. T&C Compounding’s  John Herr, RPh., has become a national expert by studying and connecting with global experts in LDN, and has helped a vast amount of patients get through chronic pain. Contact T&C to get more info.

DO YOU HAVE A QUESTION FOR A PHARMACIST?

[[[["field5","equal_to","I Have a Specific Question"]],[["show_fields","field8"]],"and"]]
1

Do You Suffer From Chronic Pain or an Autoimmune Condition?


Low Dose Naltrexone (LDN) has grown as patients' preferred alternative to addictive opioids. 

T&C LDN Experts can help refer you to a prescriber in your area & provide you with more information.

Nameyour full name
Location (City, State)your full name
Ask us any questions you might have about LDN.
0 /
Previous
Next