Brain (CNS) Inflammation
How can we quiet that brain cell activation which leads to inflammation?
According to Dr James LaValle, RG3 and Nicotinamide Riboside may help.
Read about the mechanism in which low dose naltrexone LDN works to reduce inflammation.
Abstract Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease, multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells. These effects may be unique to low dosages of naltrexone and appear to be entirely independent from naltrexone’s better-known activity on opioid receptors. As a daily oral therapy, LDN is inexpensive and well-tolerated. Despite initial promise of efficacy, the use of LDN for chronic disorders is still highly experimental. Published trials have low sample sizes, and few replications have been performed. We cover the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.
Naltrexone belongs to a class of drugs known as opioid antagonists. Naltrexone blocks opiate drugs from binding to the opioid receptors, which can result in increased endorphin and enkephalin release. Therefore, this results in reduced: 1. signaling and release of inflammatory substances, 2. nerve cell inflammation and 3. autoimmune mediators.
Low Dose Naltrexone (LDN), may be exceptionally good at reducing neuroinflammation, to the point where it could accomplish symptom reductions for neurological diseases and conditions that aren’t possible with other medications.
Speak to T&C Compounding Experts to learn more about LDN and if it could be the right fit for you or your loved one.
T&C Compounding works with the most prestigious providers. We work with you and health providers/specialists to formulate the most customized medication regimens to fit your specific needs. Medication is not one-size-fits-all, our compounding specialists use precise compounding techniques & equipment to get you the best solution.
It’s important to ask questions when researching medications, especially when it comes to pain relief. Many individuals looking for alternatives to addictive opioids have found Low Dose Naltrexone (LDN) can be the solution. T&C Compounding’s John Herr, RPh., has become a national expert by studying and connecting with global experts in LDN, and has helped a vast amount of patients get through chronic pain. Contact T&C to get more info.