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Low Dose Naltrexone (LDN)

T&C Compounding – Experts in the Compounding of LDN

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Naltrexone belongs to a class of drugs known as opioid antagonists. Naltrexone blocks opiate drugs from binding to the opioid receptors, which can result in increased endorphin and enkephalin release. Therefore, this results in reduced: 1. signaling and release of inflammatory substances, 2. nerve cell inflammation and 3. autoimmune mediators.

Which patients may benefit from LDN therapy?

Listen to LDN Radio Interviews with T&C LDN Experts.

LDN Radio: John Herr, RPh.>>

LDN Radio: Kim Hansen, RPh.>>


• Down regulates inflammatory cytokine release, oncogene expression and auto-immune cascades

• In the Central Nervous System (CNS) it reduces toll-like receptor signaling and glial cell activation resulting in reduced inflammatory cytokines and reduced neuro-inflammation

• In the Peripheral Nervous System (PNS) it modulates T & B lymphocyte production (example: gut inflammation), and reduces inflammatory cytokines (IL6, IL12, TNF alpha) and suppresses tumor growth factor (NF-kB)

When taken at bedtime, the short acting LDN binds to the receptors which leads to a brief blockade of opioid receptors between 2 am and 4 am. This blockade is believed to up-regulate vital elements of the immune system by causing an increase in endorphin and enkephalin production.

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LDN Research Trust 2020 Badge

Town & Country Compounding remains dedicated to LDN research. We continue to uphold high standards in providing quality customized medication to our community.

T&C Compounding’s Latest Blogs on Low Dose Naltrexone (LDN)

Press Release: As COVID-19 Supply Shortages Affect First Responders and Patients, New Jersey Compounders Step In

Press Release: As COVID-19 Supply Shortages Affect First Responders and Patients, New Jersey Compounders Step In

Town and Country Compounding Pharmacy Donated Hand Sanitizer to the Hoboken Police Department. .. Read More →
A Closer Look at Multiple Sclerosis

A Closer Look at Multiple Sclerosis

Multiple sclerosis (MS) is a disease of the brain and spinal cord which affects many Americans. Let's take a closer look at the.. Read More →
How Non-Opioid Medication Can Help Manage Chronic Pain

How Non-Opioid Medication Can Help Manage Chronic Pain

The opioid crisis has prompted researchers to look for alternatives to pain management. What are the alternatives, and how effective are they? .. Read More →
Ways Compounding Pharmacists Help Patients with Sjogren’s Syndrome

Ways Compounding Pharmacists Help Patients with Sjogren’s Syndrome

Diagnosed with Sjogren’s syndrome, Venus Williams, wants people with autoimmune disease to know they aren’t alone. Compounding pharmacists can help. .. Read More →
Fibromyalgia in the Spotlight

Fibromyalgia in the Spotlight

We have made progress with fibromyalgia; many doctors at least now believe it’s real. Now the challenge is how do we treat these.. Read More →
Upcoming Seminars Hosted by Town and Country Compounding

Upcoming Seminars Hosted by Town and Country Compounding

TCC's goal is to educate New Jersey about available pain management options. Learn about popular non-opioid pain treatment options from experts... Read More →
At a Loss About Weight Loss? Tips for Achieving 2020 Goals

At a Loss About Weight Loss? Tips for Achieving 2020 Goals

It’s that time of year again, everyone thinks it’s time to try harder to get their bodies to where they want. Town and.. Read More →
Why Pain & Autoimmune Patients Trust T&C Experts

Why Pain & Autoimmune Patients Trust T&C Experts

Town & Country Compounding does more than merely filling Rx's. We become partners with you and your doctor to help you try to.. Read More →
Compounding & Autoimmune Diseases: Uses of Low-Dose Naltrexone in Autoimmune Conditions

Compounding & Autoimmune Diseases: Uses of Low-Dose Naltrexone in Autoimmune Conditions

Autoimmune Diseases Can Cause a Multitude of Symptoms that negatively affect the daily lives of millions of Americans. .. Read More →

Low Dose Naltrexone (LDN) FAQ

Frequently Asked Questions

It’s important to ask questions when researching medications, especially when it comes to pain relief. Many individuals looking for alternatives to addictive opioids have found Low Dose Naltrexone (LDN) can be the solution. T&C Compounding’s  John Herr, RPh., has become a national expert by studying and connecting with global experts in LDN, and has helped a vast amount of patients get through chronic pain. Contact T&C to get more info.

Low Dose Naltrexone Dosage Forms

Find the right LDN Dosage Form for your specific needs & preferences.


The titration kit enables a patient to start their low dose naltrexone therapy and slowly ease into the dose that is appropriate for them. Kit determines personal effective dose, or maintenance dose that is right for the patient.



Taking LDN in oral capsules by mouth is the most cost-effective means of administering naltrexone and it’s the one we see most commonly prescribed. The capsules may be compounded lactose free & specific allergens can be avoided upon request. 



Naltrexone in a liquid may be prescribed for patients who may have a hard time swallowing oral capsules or for patients who may have to adjust their dose quite often or who have not yet found their perfect dose. Flavored to preference.



Some medical conditions require the topical administration of naltrexone alone or in combination with other active pharmaceutical ingredients (API’s). LDN is compounded into elegant topical cream bases that are non-irritating for the patient.



Certain medical conditions may require LDN to be administered by itself or in combination with another drug in a vaginal cream or gel.
Vaginal Applicator for LDN administrating with detailed instructions included.


Do You Need a Referral to a Low Dose Naltrexone (LDN) Prescriber?

T&C Compounding works with the most prestigious providers. We work with you and health providers/specialists to formulate the most customized medication regimens to fit your specific needs. Medication is not one-size-fits-all, our compounding specialists use precise compounding techniques & equipment to get you the best solution.

Please provide your Information to receive a list of
T&C's trusted providers, who can help you get the prescription you need.

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Low Dose Naltrexone (LDN) Success Stories

Finding solutions for chronic pain & autoimmune conditions can be a difficult process. Share your positive experience of Low Dose Naltrexone (LDN) with others that are considering and researching non-opioid options. Hearing real-life results from real patients & providers can give individuals the confidence they need.

T&C Compounding holds regular seminars connecting patients & providers with newest advancements in utilizing LDN for Chronic Pain & Autoimmune Conditions. We are always welcoming patients that have found success to share their stories with the community. We encourage you to share with individuals that may be suffering, so that they may find the relief they are looking for.

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Would you like to speak about your positive experience at one of our upcoming LDN Seminars? We’d love to have you!

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Featured LDN Review Article: The Use of Low-Dose Naltrexone (LDN)
as a Novel Anti-Inflammatory Treatment for Chronic Pain

Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease,multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells.

This review covers the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.

*Younger, J., Parkitny, L., & Mclain, D. (2014). The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain. Clinical Rheumatology, 33(4), 451-459. doi:10.1007/s10067-014-2517-2

6 Ways Naltrexone (LDN) Helps with Weight Loss

Dr. Westin Childs is dedicated to helping people with thyroid problems and hormonal imbalances in fining a solution. He is focused on personalized and functional medicine and has practiced in treating Hypothyroidism, Insulin resistance, and Leptin resistance. In this video, Dr. Westin Childs explains 6 ways Naltrexone (LDN) helps with weight loss and who should consider using it.

Tips for Achieving 2020 Weight Loss Goals

Brain (CNS) Inflammation

Recently, NBC News released a fascinating report linking central nervous system inflammation and Alzheimer’s. If true, is the first truly “attackable” angle to help prevent and potentially mitigate the symptoms of Alzheimer’s.

This could hold opportunities to advance and focus medication development towards neuroinflammation.

Low Dose Naltrexone (LDN), may be exceptionally good at reducing neuroinflammation, to the point where it could accomplish symptom reductions for neurological diseases and conditions that aren’t possible with other medications.

Lyme Disease Documentary with Mention of Low Dose Naltrexone (LDN)

What is Lyme Disease? How do you catch it? How to get an accurate diagnosis? How to treat it? How to live with it? What are options for alleviating symptoms?

Low Dose Naltrexone (LDN) is a treatment option that has grown globally in popularity for treating a variety of conditions, including lyme disease.

Watch Video: Lyme Disease & LDN

Upcoming Informational Seminars

RSVP for our next informational seminar.

Upcoming T&C Webinars

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Do You Suffer From Chronic Pain or an Autoimmune Condition?

Low Dose Naltrexone (LDN) has grown as patients' preferred alternative to addictive opioids. 

T&C LDN Experts can help refer you to a prescriber in your area & provide you with more information.

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