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Low Dose Naltrexone (LDN)

T&C Compounding – Experts in the Compounding of LDN

WHAT IS LOW DOSE NALTREXONE (LDN)?

Naltrexone belongs to a class of drugs known as opioid antagonists. Naltrexone blocks opiate drugs from binding to the opioid receptors, which can result in increased endorphin and enkephalin release. Therefore, this results in reduced: 1. signaling and release of inflammatory substances, 2. nerve cell inflammation and 3. autoimmune mediators.

Which patients may benefit from LDN therapy?

Listen to LDN Radio Interview with New Jersey LDN Expert John Herr, RPh.

Listen Here >>

HOW DOES LDN WORK?

• Down regulates inflammatory cytokine release, oncogene expression and auto-immune cascades

• In the Central Nervous System (CNS) it reduces toll-like receptor signaling and glial cell activation resulting in reduced inflammatory cytokines and reduced neuro-inflammation

• In the Peripheral Nervous System (PNS) it modulates T & B lymphocyte production (example: gut inflammation), and reduces inflammatory cytokines (IL6, IL12, TNF alpha) and suppresses tumor growth factor (NF-kB)

When taken at bedtime, the short acting LDN binds to the receptors which leads to a brief blockade of opioid receptors between 2 am and 4 am. This blockade is believed to up-regulate vital elements of the immune system by causing an increase in endorphin and enkephalin production.

Low Dose Naltrexone (LDN) FAQ

Frequently Asked Questions

It’s important to ask questions when researching medications, especially when it comes to pain relief. Many individuals looking for alternatives to addictive opioids have found Low Dose Naltrexone (LDN) can be the solution. T&C Compounding’s  John Herr, RPh., has become a national expert by studying and connecting with global experts in LDN, and has helped a vast amount of patients get through chronic pain. Contact T&C to get more info.

Low Dose Naltrexone Dosage Forms

Find the right LDN Dosage Form for your specific needs & preferences.

LDN TITRATION KIT – CAPSULES

The titration kit enables a patient to start their low dose naltrexone therapy and slowly ease into the dose that is appropriate for them. Kit determines personal effective dose, or maintenance dose that is right for the patient.

LDN TITRATION KIT

LDN CAPSULES

Taking LDN in oral capsules by mouth is the most cost-effective means of administering naltrexone and it’s the one we see most commonly prescribed. The capsules may be compounded lactose free & specific allergens can be avoided upon request. 

LDN CAPSULES

LDN ORAL LIQUID

Naltrexone in a liquid may be prescribed for patients who may have a hard time swallowing oral capsules or for patients who may have to adjust their dose quite often or who have not yet found their perfect dose. Flavored to preference.

ORAL LIQUID LDN

TOPICAL LDN IN CREAM

Some medical conditions require the topical administration of naltrexone alone or in combination with other active pharmaceutical ingredients (API’s). LDN is compounded into elegant topical cream bases that are non-irritating for the patient.

TOPICAL LDN

LDN IN VAGINAL CREAM/GEL

Certain medical conditions may require LDN to be administered by itself or in combination with another drug in a vaginal cream or gel.
Vaginal Applicator for LDN administrating with detailed instructions included.

VAGINAL LDN

Do You Need a Referral to a Low Dose Naltrexone (LDN) Prescriber?

T&C Compounding works with the most prestigious providers. We work with you and health providers/specialists to formulate the most customized medication regimens to fit your specific needs. Medication is not one-size-fits-all, our compounding specialists use precise compounding techniques & equipment to get you the best solution.

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Low Dose Naltrexone (LDN) Success Stories

Finding solutions for chronic pain & autoimmune conditions can be a difficult process. Share your positive experience of Low Dose Naltrexone (LDN) with others that are considering and researching non-opioid options. Hearing real-life results from real patients & providers can give individuals the confidence they need.

T&C Compounding holds regular seminars connecting patients & providers with newest advancements in utilizing LDN for Chronic Pain & Autoimmune Conditions. We are always welcoming patients that have found success to share their stories with the community. We encourage you to share with individuals that may be suffering, so that they may find the relief they are looking for.

Submit Testimonial

Would you like to speak about your positive experience at one of our upcoming LDN Seminars? We’d love to have you!

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Featured LDN Review Article: The Use of Low-Dose Naltrexone (LDN)
as a Novel Anti-Inflammatory Treatment for Chronic Pain

Low-dose naltrexone (LDN) has been demonstrated to reduce symptom severity in conditions such as fibromyalgia, Crohn’s disease,multiple sclerosis, and complex regional pain syndrome. We review the evidence that LDN may operate as a novel anti-inflammatory agent in the central nervous system, via action on microglial cells.

This review covers the typical usage of LDN in clinical trials, caveats to using the medication, and recommendations for future research and clinical work. LDN may represent one of the first glial cell modulators to be used for the management of chronic pain disorders.

*Younger, J., Parkitny, L., & Mclain, D. (2014). The use of low-dose naltrexone (LDN) as a novel anti-inflammatory treatment for chronic pain. Clinical Rheumatology, 33(4), 451-459. doi:10.1007/s10067-014-2517-2

LOW DOSE NALTREXONE (LDN) RESOURCES | RECOMMENDED BY NEW JERSEY LOW DOSE NALTREXONE EXPERTS

Brain (CNS) Inflammation

Recently, NBC News released a fascinating report linking central nervous system inflammation and Alzheimer’s. If true, is the first truly “attackable” angle to help prevent and potentially mitigate the symptoms of Alzheimer’s.

This could hold opportunities to advance and focus medication development towards neuroinflammation.

Low Dose Naltrexone (LDN), may be exceptionally good at reducing neuroinflammation, to the point where it could accomplish symptom reductions for neurological diseases and conditions that aren’t possible with other medications.

Lyme Disease Documentary with Mention of Low Dose Naltrexone (LDN)

What is Lyme Disease? How do you catch it? How to get an accurate diagnosis? How to treat it? How to live with it? What are options for alleviating symptoms?

Low Dose Naltrexone (LDN) is a treatment option that has grown globally in popularity for treating a variety of conditions, including lyme disease.

Watch Video: Lyme Disease & LDN

Upcoming Informational Seminars

RSVP for our next informational seminar.

Read Latest Articles on Low Dose Naltrexone

Fibromyalgia in the Spotlight

Fibromyalgia in the Spotlight

We have made progress with fibromyalgia; many doctors at least now believe it’s real. Now the challenge is how do we treat these.. Read More →
T&C Pharmacists Attend LDN Conference in Portland, Oregon

T&C Pharmacists Attend LDN Conference in Portland, Oregon

While Low Dose Naltrexone is more widely known as an opioid alternative for pain management, researchers have found more ways to utilize it... Read More →
Lyme Disease & Low Dose Naltrexone (LDN)

Lyme Disease & Low Dose Naltrexone (LDN)

Addressing immune dysfunction could be key to treating Chronic Lyme Disease. T&C Compounding Experts work with physicians/patients for the right treatment... Read More →
DO YOU HAVE A QUESTION FOR A PHARMACIST?

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Do You Suffer From Chronic Pain?


Low Dose Naltrexone (LDN) has grown as patients' preferred alternative to addictive opioids. 

T&C LDN Experts can help refer you to a prescriber in your area & provide you with more information.

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